MACSima™ Imaging Platform - The easy way to ultrahigh-content imaging
 
The MACSima Imaging Platform can enables fully automated high-content imaging. The possibility of evaluating localization, expression, and potential interaction of a multitude of different proteins allows scientists to tap the full potential of spatial biology.
 
MACSima Imaging Cyclic Staining (MICS) technology enables the simultaneous analysis of hundreds of markers on a single sample based on fluorescence microscopy. It uses the principle of iterative staining with different fluorochrome-conjugated antibodies to acquire microscopy data for a multitude of parameters without harming the sample. The iterative process comprises three main steps: fluorescent staining, image acquisition, and erasure of the fluorescence signal, all of which are conducted by the MACSima Imaging System in a fully automated manner. The resulting stack of potentially hundreds of marker images provides an unprecedented insight into the physiological or pathological characteristics of the sample. Due to on-the-fly processing, data analysis can start at any time, even when the iterative process is still running.